Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Adjunct to levodopa treatment in Parkinson's disease
Age: Adult
Dose: Oral – 200 mg
Frequency: with each levodopa/dopa decarboxylase inhibitor dose
Note: Maximum: 200 mg 10 times daily (2,000 mg daily).
Condition: Hepatic Impairment
Dose: Oral
Note: Safety and efficacy not established

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: No approved pediatric dosage available
Note: No approved pediatric dosage available

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment
Dose: Renal Dose
Note: Dosage adjustment not necessary
Administration
  • Take with or without food
  • Take with each levodopa dose
Side Effect

Drug Interaction

Drug NameRisk Factors
Adrenaline, Apomorphine, Dobutamine, Dopamine, Isoprenaline, Methyldopa, Noradrenaline, Remiterol
May affect metabolism
Iron preparations, Levodopa
Interaction

Disease Interaction

Disease NameRisk Factors
History of Neuroleptic Malignant Syndrome
Risk of recurrence
History of Nontraumatic Rhabdomyolysis
Risk of muscle breakdown

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 25°C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.