Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Menopausal hormone replacement therapy Age: Adult |
Dose: Oral – 0.5-3 mg Frequency: daily Duration: for 1 month followed by 0.5-1 mg daily Note: Or 0.25-2 mg daily in combination with other natural oestrogens. A progestogen is required if administered to women with a uterus. |
|
Indication: Infertility due to cervical hostility Age: Adult |
Dose: Oral – 0.25-1 mg/day Duration: on days 6-15 of the menstrual cycle Note: Increase dose each month until an optimal effect is obtained. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Osteoporosis, osteomalacia, rickets, tetany, and parathyroid disease Age: Adult |
Dose: Tablet – 500 mg Calcium and 200 IU Vitamin D3 Frequency: twice daily Note: 2 tablets daily or 1 tablet twice daily; best taken with or just after a meal to improve absorption |
|
Indication: Osteoporosis, osteomalacia, rickets, tetany, and parathyroid disease Age: Adult |
Dose: Tablet – 500 mg Calcium and 400 IU Vitamin D3 Frequency: twice daily Note: 1 tablet twice daily; best taken with or just after a meal to improve absorption |
Administration
- May be taken with or without food
- Take at same time daily
Side Effect
- Breast tension or pain
- nausea
- spotting
- Fluid retention
- cervical hypersecretion
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Activated charcoal, Barbiturates, Carbamazepine, Phenobarbital, Phenytoin, Griseofulvin, Hydantoin, Rifampicin
|
Reduced efficacy
|
|
Oral Anticoagulants (Warfarin, Heparin, Dabigatran, Rivaroxaban, Apixaban, Edoxaban)
|
May possibly change efficacy
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Acute Liver Disease
|
Can worsen liver function
|
|
Known/Past/Suspected Breast Cancer
|
Can stimulate cancer growth
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.