Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Absence seizures
Age: Adult
Dose: Oral – Initially, 500 mg
Frequency: daily
Note: May increase in steps of 250 mg at intervals of 4-7 days. Usual dose: 1-1.5 g daily. Maximum: Up to 2 g in some patients. Strict supervision is recommended if dose greater than 1.5 g daily. Optimum plasma concentration: 40-100 mg/L (300-700 micromol/L).
Indication: Absence seizures
Age: Adult
Condition: Hepatic Impairment
Dose: Oral
Note: Monitor closely

Child Dose

Clinical InformationAdministration Information
Age: Children
Dose: Oral – 50 mg/kg/day
Frequency: every 6 to 8 hours
Note: by mouth (oral)

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment
Dose: Not specified
Note: Monitor closely
Administration
  • Take with food
  • Take with water
Side Effect

Drug Interaction

Drug NameRisk Factors
Isoniazid
May increase serum concentration, leading to toxicity
Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole), Antidepressants (Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram, Venlafaxine, Duloxetine), MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide), Mefloquine
May antagonise anticonvulsant effects

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.