Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Influenza A Age: Adult |
Dose: Oral – 100 mg Frequency: by mouth Duration: for 5 days |
|
Indication: Prophylaxis of influenza A Age: Adult |
Dose: Oral – 100 mg Frequency: once daily Duration: for up to 6 weeks |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Influenza A treatment Age: 1-9 years or less than 40 kg (any age) |
Dose: Oral – 5 mg/kg/day Frequency: single dose or divided every 12 hours Note: by mouth (oral); not to exceed 150 mg/day; Because of resistance, amantadine is no longer recommended for prophylaxis or treatment of influenza A |
|
Indication: Influenza A treatment Age: greater than 10 years |
Dose: Oral – 5 mg/kg/day Frequency: divided every 12 hours Note: by mouth (oral); Because of resistance, amantadine is no longer recommended for prophylaxis or treatment of influenza A |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment with Creatinine Clearance greater than 35 ml/min |
Dose: Tablet – 100 mg Frequency: once daily |
|
Condition: Renal impairment with Creatinine Clearance 15-35 ml/min |
Dose: Tablet – 100 mg Frequency: every 2-3 days |
Administration
- Take with food
- Take at same times daily
Side Effect
- Agitation
- Anorexia
- Anxiety
- Ataxia
- Confusion
- Constipation
- Depression
- Diarrhea
- Dizziness
- Dream abnormality
- Dry nose
- Fatigue
- Hallucinations
- Headache
- Insomnia
- Irritability
- Livedo reticularis
- Nausea
- Nervousness
- Orthostatic hypotension
- Peripheral edema
- Somnolence
- Xerostomia
- Amnesia
- CHF
- Decreased libido
- Dyspnea
- Eczematoid dermatitis
- Euphoria
- Hyperkinesis
- Hypertension
- Instances of convulsions
- Leukopenia
- Neutropenia
- Oculogyric episodes
- Psychosis
- Rash
- Slurred speech
- Urinary retention
- Visual disturbances
- Vomiting
- Weakness
- Congestive heart failure
- convulsions
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antimuscarinics (Atropine, Hyoscine, Ipratropium), Levodopa
|
Enhances the adverse effects
|
|
CNS stimulants
|
Interaction noted
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Epilepsy, Seizure Disorders
|
Can trigger seizures
|
|
Severe Renal Impairment
|
Risk of drug toxicity
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 20-25°C in dry place. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.