Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Seasonal Allergic Rhinitis with Nasal Congestion Age: Adult |
Dose: Tablet – 1 tablet (60 mg fexofenadine / 120 mg pseudoephedrine) Frequency: twice daily Note: by mouth (oral) |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: greater than 12 years |
Dose: Tablet – 1 tablet Frequency: twice daily |
|
Age: less than 12 years |
Dose: Dose: Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Avoid Note: Avoid use in patients with renal impairment |
Administration
- Take with water only
- Do not crush or chew tablet
Side Effect
- Headache (7.2%)
- Drowsiness (1.3%)
- Fatigue (1.3%)
- CNS depression
- Sedation ranging from mild drowsiness to deep sleep (most frequent)
- Dizziness
- Lassitude
- Disturbed coordination
- Muscular weakness
- Restlessness
- insomnia
- tremors
- euphoria
- nervousness
- delirium
- palpitation
- seizures is less common
- Epigastric distress
- Anorexia
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Cholestasis
- hepatitis
- hepatic failure
- hepatic function abnormality
- jaundice is rare
- Tachycardia
- palpitation ECG changes (eg widened QRS)
- Arrhythmias (eg extrasystole, heart block)
- Hypotension
- Hypertension
- Dizziness
- sedation
- and hypotension may occur in geriatric patients
- Dryness of mouth
- nose
- and throat
- Dysuria
- Urinary retention
- Impotence
- Vertigo
- Visual disturbances
- Blurred vision
- Diplopia
- tinnitus
- Acute labyrinthitis
- Tremors
- Nervousness
- Irritability
- Facial dyskinesia
- Tightness of the chest
- Thickening of bronchial secretions
- Wheezing
- Nasal stuffiness
- Sweating
- Chills
- Early menses
- Toxic psychosis
- Faintness
- Paresthesia
- Agranulocytosis
- Hemolytic anemia
- Leukopenia
- Thrombocytopenia
- Pancytopenia
- Dysmenorrhea
- Dyspepsia
- Fatigue
- Ischemic colitis (pseudoephedrine)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Cardiac glycosides, Quinidine, TCAs
|
Increased risk of hypertension and arrhythmias
|
|
Ergot alkaloids, Oxytocin
|
Increased risk of vasoconstrictor effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Hypertension
|
Can increase blood pressure
|
|
Phaeochromocytoma
|
Can cause hypertensive crisis
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at a cool and dry place, protected from light & moisture. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.