Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Resistant Hypertension
Age: Adult
Dose: Oral – 20-80 mg
Frequency: every 12 hours
Note: administered by mouth
Indication: Edema associated with congestive heart failure (CHF), liver cirrhosis, and renal disease, including nephrotic syndrome
Age: Adult
Dose: Oral – 20-80 mg
Frequency: once daily
Note: administered by mouth; may be increased by 20-40 mg every 6-8 hours; not to exceed 600 mg/day

Child Dose

Clinical InformationAdministration Information
Indication: Edema
Age: Infants and children
Dose: Intravenous, Intramuscular, or By mouth (oral) – 1-2 mg/kg
Frequency: once initially
Note: individual dose not to exceed 6 mg/kg
Indication: Edema
Age: Infants and children
Condition: Dosage increase
Dose: By mouth (oral) – 1-2 mg/kg
Frequency: every 6-8 hours
Note: individual dose not to exceed 6 mg/kg

Renal Dose

Clinical InformationAdministration Information
Condition: Acute renal failure
Dose: 1-3 g/day
Note: may be necessary to attain desired response; avoid use in oliguric states
Administration
  • Can take with/without food
  • Take in morning
Side Effect

Drug Interaction

Drug NameRisk Factors
Analgesics
Reduce natriuretic action
Hypoglycaemic agents, Drugs used for gout
Antagonises effects

Disease Interaction

Disease NameRisk Factors
Severe Sodium And Water Depletion
Can worsen dehydration
Hypokalaemia, Hyponatraemia
Can cause dangerous electrolyte imbalance

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Protect from light. Do not use it later than the date of expiry. Keep all medicines out of the reach of children. To be dispensed only on the prescription of a registered physician.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.