Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult |
Dose: Tablet – amiloride hydrochloride 2.5 mg and hydrochlorothiazide 25 mg Frequency: Initially 1 tablet daily Note: Increased up to a maximum of 2 tablets daily as a single or divided dose |
|
Indication: Hypertension Age: Adult |
Dose: Tablet – amiloride hydrochloride 5 mg and hydrochlorothiazide 50 mg Frequency: Initially 1/2 tablet daily Note: Increased up to a maximum of 1 tablet daily as a single or divided dose |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Tablet – No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal Impairment |
Dose: Dose: Note: Use caution in patients with diabetes mellitus or serum creatinine greater than 1.5 mg/dL; contraindicated in anuria, acute or chronic renal insufficiency or signs of diabetic nephropathy |
Administration
- Take with food
- Take in morning
Side Effect
- Hyperkalemia (10%)
- Anorexia (3-8%)
- Diarrhea (3-8%)
- Headache (3-8%)
- Nausea (3-8%)
- Vomiting (3-8%)
- Abdominal pain (Less than 3%)
- Appetite changes (Less than 3%)
- Constipation (Less than 3%)
- Cough (Less than 3%)
- Dizziness (Less than 3%)
- Dyspnea (Less than 3%)
- Encephalopathy (Less than 3%)
- Fatigue (Less than 3%)
- Gas pain (Less than 3%)
- Impotence (Less than 3%)
- Muscle cramps (Less than 3%)
- Weakness (Less than 3%)
- Hypotension
- Anorexia
- Epigastric distress
- Hypokalemia
- Phototoxicity
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Other Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil)
|
Additive effects
|
|
Tubocurarine
|
May increase the responsiveness
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hyperkalaemia
|
Dangerous potassium elevation
|
|
Anuria, Acute Renal Failure
|
Risk of kidney complications
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 20 to 25°C
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.