Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Acute bacterial exacerbation of chronic bronchitis Age: Adult |
Dose: Oral – 320 mg Frequency: once daily Duration: 5 days |
|
Indication: Community-acquired pneumonia Age: Adult Condition: Mild to moderate |
Dose: Oral – 320 mg Frequency: once daily Duration: 7 days |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment: Creatinine Clearance (ml/min) less than 40 (or patient on haemodialysis/CAPD) |
Dose: Tablet – 160 mg Frequency: once daily Note: CAPD refers to continuous ambulatory peritoneal dialysis |
Administration
- Can take with/without food
- Take with water
Side Effect
- Diarrhea (5%)
- Headache (4%)
- Nausea (4%)
- Rash (4%)
- Transaminases increased (1-4%)
- Abdominal pain (2%)
- Dizziness (2%)
- Vomiting (2%)
- Neutropenia (1%)
- Platelets increased (1%)
- Thrombocythemia (1%)
- GGT increased (1%)
- Peripheral neuropathy
- Photosensitivity
- Tendon rupture
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Class IA (e.g. quinidine) or class III (e.g. amiodarone) Antiarrhythmics (Amiodarone, Flecainide, Propafenone, Quinidine, Disopyramide, Procainamide), Other drugs that prolong QT interval (e.g. erythromycin, TCAs, antipsychotic agents)
|
Additive effect on QT interval prolongation
|
|
Probenecid
|
Renal clearance reduced
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.