Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Treatment and prophylaxis of haemorrhage Age: Adult |
Dose: Intravenous – Initially, 4-5 g as a 2% solution Frequency: followed by a 1 g/hour infusion Duration: over 1 hour followed by infusion continued for up to 8 hours or until bleeding has been controlled Note: Maximum: 24 g in 24 hours. |
|
Indication: Treatment and prophylaxis of haemorrhage Age: Adult |
Dose: Oral – Initially, 4-5 g Frequency: followed by 1-1.25 g every hour Duration: for about 8 hours or until bleeding has been controlled Note: Maximum: 24 g in 24 hours. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Form – No approved pediatric dosage available Note: There is no approved pediatric dosage for this drug |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dosage reduction may be required Note: Renal impairment: Dosage reduction may be required. |
Administration
- Take with or without food
- Take with water
Side Effect
- Oedema
- headache
- malaise
- allergic and anaphylactic reactions
- anaphylaxis
- bradycardia
- hypotension
- peripheral ischaemia
- thrombosis
- abdominal pain
- diarrhoea
- nausea
- vomiting
- agranulocytosis
- coagulation disorder
- leukopaenia
- thrombocytopaenia
- increased CPK
- muscle damage
- myalgia
- myopathy
- myositis
- rhabdomyolysis
- confusion
- convulsions
- delirium
- dizziness
- hallucinations
- intracranial hypertension
- stroke
- syncope
- dyspnoea
- nasal congestion
- pulmonary embolism
- pruritus
- rash
- tinnitus
- decreased vision
- watery eyes
- increased BUN
- dry ejaculation
- Cardiac and hepatic damage
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Oral contraceptives, Oestrogens
|
Increased risk of hypercoagulability
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Disseminated Intravascular Coagulation
|
Can worsen blood clotting disorder
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool, dry place, protected from light. Store the suspension below 30° C. Keep out of reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.