Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Induction of general anaesthesia Age: Adult |
Dose: Inhalation – 0.5% v/v of halothane in oxygen or mixture of nitrous oxide and oxygen, increase gradually according to response to a concentration of 2-4% v/v Note: Increase gradually according to response |
|
Indication: Maintenance of general anaesthesia Age: Adult |
Dose: Inhalation – 0.5-2% v/v Note: Depending on the flow rate used |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Induction of general anaesthesia Age: Child |
Dose: Inhalation – 1.5-2% volume by volume |
|
Indication: Maintenance of general anaesthesia Age: Child |
Dose: Inhalation – 0.5-1.5% volume by volume |
Administration
- Hospital use only
- Given by anesthetist
Side Effect
- Post-op nausea
- vomiting
- and shivering
- resp depression
- hypotension
- skeletal muscle relaxation
- bradycardia
- Hepatotoxicity
- malignant hyperthermia
- cardiac arrhythmias
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Epinephrine
|
Increased risk of ventricular dysrhythmias
|
|
Suxamethonium
|
Increased risk of malignant hyperthermia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Malignant Hyperthermia
|
Can trigger life-threatening reactions
|
|
Raised CSF Pressure
|
Can increase brain pressure
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Bottles of Halothane must be securely closed and stored in a cool dry place, protected from light. Halothane must be kept in the original container until immediately prior to its use.
Whilst in the liquid phase, Halothane must not be diluted or contaminated; however, in the vapour phase it may be administered together with Oxygen or a mixture of Nitrous Oxide and Oxygen.
Whilst in the liquid phase, Halothane must not be diluted or contaminated; however, in the vapour phase it may be administered together with Oxygen or a mixture of Nitrous Oxide and Oxygen.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.