Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Hypertension
Age: Adult
Dose: Oral – Initially, 12.5 mg, may increase to 25-50 mg
Frequency: once daily
Note: titrate as necessary either alone or with other antihypertensives
Indication: Hypertension
Age: Elderly
Dose: Oral – 12.5-25 mg
Frequency: once daily
Note: titrate as necessary in increments of 12.5 mg

Child Dose

Clinical InformationAdministration Information
Indication: Hypertension
Age: less than 6 month
Dose: Oral – 1-3 mg/kg/day
Frequency: in 1-2 divided doses
Note: Maximum: 37.5 mg daily
Indication: Hypertension
Age: 6 month to 2 year
Dose: Oral – 1-2 mg/kg/day
Frequency: in 1-2 divided doses
Note: Maximum: 37.5 mg daily

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment Creatinine Clearance less than 10 mL/min
Dose: Not specified
Note: Avoid use
Condition: Renal impairment Creatinine Clearance greater than 10 mL/min
Dose: Not specified
Note: Dose adjustment not necessary; not effective with Creatinine Clearance less than 30 mL/min unless used in combination with loop diuretic
Administration
  • Take with food
  • Same time daily
Side Effect

Drug Interaction

Drug NameRisk Factors
Lithium
Increases toxicity
Barbiturates, Narcotics
May potentiate orthostatic hypotension

Disease Interaction

Disease NameRisk Factors
Anuria
Can worsen kidney function
Severe Renal Impairment
Can cause electrolyte imbalance

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30°C. Protect from light, moisture and freezing.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.