Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Essential hypertension Age: Adult |
Dose: Oral Tablet – Per tablet contains ramipril 2.5 mg and hydrochlorothiazide 12.5 mg Frequency: 1 tablet daily Note: Maximum of 4 tablets daily. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Take at same time daily
- Can take with/without food
Side Effect
- Pancreatitis
- jaundice
- diarrhoea
- nausea
- vomiting
- cramps
- constipation
- gastric irritation
- anorexia
- aplastic anaemia
- agranulocytosis
- leukopaenia
- haemolytic anaemia
- thrombocytopaenia
- vasculitis
- resp distress
- including pneumonitis and pulmonary oedema
- photosensitivity
- fever
- urticaria
- rash
- hyperglycaemia
- glycosuria
- hyperuricaemia
- muscle spasm
- vertigo
- paraesthesias
- dizziness
- headache
- restlessness
- renal failure
- renal dysfunction
- interstitial nephritis
- erythema multiforme including Stevens-Johnson syndrome
- exfoliative dermatitis including toxic epidermal necrolysis
- alopoecia
- transient blurred vision
- xanthopsia
- impotence
- dizziness
- fatigue
- headache
- abdominal pain
- cough
- rarely symptomatic hypotension
- angioneurotic oedema of face
- lips
- tongue
- glottis and larynx
- syncope
- renal impairment
- hypersensitivity reactions
- Anaphylactic reactions
- electrolyte imbalance
- hypotension
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Alcohol, Barbiturates, Narcotics
|
Potentiates orthostatic hypotension
|
|
Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil)
|
Additive effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Anuria
|
Can worsen kidney function
|
|
History Of Angioedema
|
Can trigger severe allergic reaction
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.