Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension |
Dose: Tablet/Capsule – 1-2 tablets/capsules (37.5-50 mg triamterene and 25 mg hydrochlorothiazide) Frequency: once daily Note: by mouth; Monitor serum potassium |
|
Indication: Hypertension |
Dose: Tablet – 1 tablet (75 mg triamterene and 50 mg hydrochlorothiazide) Frequency: once daily Note: by mouth; Monitor serum potassium |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Take with food
- Take in morning
Side Effect
- Jaundice
- Weaknes
- Headache
- Azotemia
- Dizziness
- Fatigue
- Xerostomia
- Photosensitivity
- Rash
- Diarrhea
- Nausea
- Vomiting
- Hyperuricemia
- Hyper/hypokalemia
- Interstitial nephritis
- Anorexia
- Epigastric distress
- Hypotension
- Orthostatic hypotension
- Photosensitivity
- Anaphylaxis
- Anemia
- Confusion
- Erythema multiforme
- Stevens-Johnson syndrome
- Exfoliative dermatitis including toxic epidermal necrolysis
- Dizziness
- Hypokalemia and/or hypomagnesemia
- Hyperuricemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Digitalis glycosides
|
May enhance toxicity
|
|
Competitive Muscle Relaxants (Baclofen, Cyclobenzaprine, Tizanidine, Dantrolene)
|
May enhance neuromuscular-blocking action
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Severe Renal Impairment
|
Can cause drug toxicity
|
|
Severe Hepatic Impairment
|
Can cause drug accumulation
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25°C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.