Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Depression
Age: Adult
Dose: Oral – Initially, 75 mg
Frequency: in divided doses
Note: may gradually increase to 150-200 mg daily as necessary. Maximum: 300 mg/day. May give in divided doses or single dose at bedtime.
Indication: Depression
Age: Adult
Condition: Maintenance dose
Dose: Oral – 50-100 mg
Frequency: once daily by mouth

Child Dose

Clinical InformationAdministration Information
Indication: Nocturnal enuresis
Age: 6-7 years
Dose: Oral – 25 mg
Frequency: once daily
Duration: Maximum treatment duration: 3 months
Note: Doses are given just before bedtime
Indication: Nocturnal enuresis
Age: 8-11 years
Dose: Oral – 25-50 mg
Frequency: once daily
Duration: Maximum treatment duration: 3 months
Note: Doses are given just before bedtime
Administration
  • Can take with/without food
  • Regular timing
Side Effect

Drug Interaction

Drug NameRisk Factors
Quinidine, Cimetidine, SSRIs, Propafenone, Flecainide
Increased plasma levels and effects
Barbiturates, Phenytoin
Reduced plasma levels

Disease Interaction

Disease NameRisk Factors
Heart Block Or Cardiac Arrhythmias
Can worsen heart rhythm
Recent MI
Can stress heart

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.