Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hypertension Age: Adult |
Dose: Oral – 1.25-2.5 mg Frequency: once daily Note: alone or in conjunction with other antihypertensives |
|
Indication: Oedema Age: Adult |
Dose: Oral – 2.5 mg Frequency: once daily Note: increased to 5 mg daily after 1 week if needed |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Take with food
- Take in morning
Side Effect
- Hypotension
- Palpation
- Flushing
- Dizziness
- Lightheadedness
- Vertigo
- Headache
- Weakness
- Restlessness
- Drowsiness
- Fatigue
- Lethargy
- Malaise
- Anorexia
- Nausea/vomiting
- Nocturia
- Polyuria
- Blurred vision
- Rhinnorhea
- Electrolyte abnormalities
- Pruritus
- Rash
- Cutaneous vasculitis
- Glycosuria
- Pancreatitis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil), Diuretics
|
Additive effect
|
|
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), Corticotropin, Amphotericin
|
Increased chance of hypokalaemia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Anuria
|
Can worsen kidney function
|
|
Severe Hepatic Impairment
|
Can affect drug metabolism
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place. Protect from light and moisture.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.