Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Renal cell carcinoma Age: Adult Condition: As an adjunct to cytotoxic chemotherapy |
Dose: Subcutaneous – 3 million units Frequency: 3 times weekly Duration: 1 week Note: Escalating dose |
|
Indication: Renal cell carcinoma Age: Adult Condition: As an adjunct to cytotoxic chemotherapy |
Dose: Subcutaneous – 9 million units Frequency: 3 times weekly Duration: 1 week Note: Escalating dose |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic hepatitis C Age: 5 years of age and older |
Dose: Subcutaneous Injection – 180 mcg/1.73 m2 x body surface area Frequency: Once weekly Note: Subcutaneous |
|
Indication: Chronic hepatitis B Age: 3 years of age and older |
Dose: Subcutaneous Injection – 180 mcg/1.73 m2 x body surface area Frequency: Once weekly Note: Subcutaneous |
Administration
- Given by injection
- Medical supervision needed
Side Effect
- Depressive illness
- suicidal behaviour
- irritability
- insomnia
- anxiety
- Flu-like symptoms
- Headache
- dizziness
- paraesthesia
- confusion
- impaired concentration
- alteration in taste or smell
- GI disturbances
- Dryness of oropharynx
- epistaxis
- rhinitis
- arrhythmia
- sinusitis
- Injection site reaction
- alopecia
- rash
- dry skin or pruritus
- Conjunctivitis
- menstrual irregularity
- visual disturbances
- Coughing
- dyspnoea
- Myalgia
- joint or bone pain
- arthritis or polyarthritis
- Bone marrow depression
- Marked increase in triglyceride levels
- GI haemorrhage
- severe infections
- pulmonary infiltrates or pulmonary function impairment
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Theophylline
|
Reduces clearance
|
|
Zidovudine, Ganciclovir, Valganciclovir, Dapsone, Doxorubicin, Vincristine, Vinblastine
|
Enhanced myelosuppression
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Autoimmune Hepatitis
|
Can worsen liver inflammation
|
|
Hepatic Decompensation
|
Can worsen liver function
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.