Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chronic obstructive pulmonary disease Age: Adult |
Dose: Metered-dose inhaler – 100 mcg/20 mcg (1 actuation) Frequency: every 6 hours Note: Not to exceed 6 actuations per day |
|
Indication: Chronic obstructive pulmonary disease Age: Adult |
Dose: Nebulizer solution – 3 ml Frequency: initially every 6 hours Note: Maximum 3 ml every 4 hours |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Administration
- Follow inhaler technique
- Rinse mouth after use
Side Effect
- Bronchitis (2-12%)
- Upper respiratory tract infection (URTI) (1-10%)
- Lung disease (6%)
- Headache (3-6%)
- Dyspnea (2-5%)
- Nasopharyngitis (4%)
- Cough (3-4%)
- Pharyngitis (2-4%)
- Pain (1-3%)
- Chest pain (2.6%)
- Sinusitis (2.3%)
- Nausea (1-2%)
- Diarrhea (1.8%)
- Urinary Tract Infection (UTI) (1.6%)
- Influenza (1.4%)
- Leg cramps (1.4%)
- Nausea (1.4%)
- Pneumonia (1.4%)
- Rhinitis (1.1%)
- Allergic-type reactions
- such as skin reactions (eg rash, pruritus, urticaria [including giant urticaria])
- angioedema (eg of tongue, lips, face)
- laryngospasm
- and anaphylaxis
- Angina
- Arrhythmia
- Arthralgia
- Dizziness
- Dry mouth
- Dyspepsia
- Dysphonia
- Edema
- Fatigue
- Hypertension
- Insomnia
- Nervousness
- Palpitation
- Paresthesia
- Tachycardia
- Tremor
- Vomiting
- Anaphylactic reactions such as angioedema of tongue
- lips or face and laryngospasm
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Psychotropics
|
May have additive anticholinergic effects
|
|
Propranolol
|
May decrease effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypertrophic Obstructive Cardiomyopathy
|
Can worsen heart condition
|
|
Tachyarrhythmia
|
Can increase irregular heartbeat
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Do not puncture, break or incinerate the pressurized canister even when apparently empty. Avoid storage in direct sunlight or heat. Store in a cool and dry place. Keep away from children. Keep away from eyes.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.