Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Anxiety Disorders
Age: Adult
Dose: Oral – 1-6 mg/day
Frequency: in 2 or 3 divided doses
Note: Maximum 10 mg/day. Elderly: Half the usual adult dose or less. Hepatic impairment (Mild to moderate): May require reduced doses. Hepatic impairment (Severe): Contraindicated.
Indication: Insomnia associated with anxiety
Age: Adult
Dose: Oral – 1-4 mg/day
Frequency: at bedtime
Note: Elderly: Half the usual adult dose or less. Hepatic impairment (Mild to moderate): May require reduced doses. Hepatic impairment (Severe): Contraindicated.

Child Dose

Clinical InformationAdministration Information
Indication: Status Epilepticus
Age: Infants and children
Dose: Intravenous – 0.05-0.1 mg/kg
Duration: over 2-5 minutes
Note: not to exceed 4 mg/dose; may repeat every 10-15 minutes as needed
Indication: Status Epilepticus
Age: Infants and children
Dose: Intravenous – 0.1 mg/kg
Note: slow intravenous rate not to exceed rate of 2 mg/minute; not to exceed dose of 4 mg

Renal Dose

Clinical InformationAdministration Information
Condition: Renal impairment
Dose: by mouth (oral) – Dose adjustment not necessary
Note: Renal impairment
Condition: Mild-to-moderate renal impairment
Dose: intravenous/intramuscular – Use with caution
Note: Renal impairment
Administration
  • Can take with/without food
  • Regular timing
Side Effect

Drug Interaction

Drug NameRisk Factors
Barbiturates, Phenothiazines, Antidepressants (Fluoxetine, Sertraline, Paroxetine, Citalopram, Escitalopram, Venlafaxine, Duloxetine), MAOIs (Phenelzine, Tranylcypromine, Selegiline, Moclobemide)
Additive CNS effects
Scopolamine
May increase sedation, hallucinations and irrational behaviour

Disease Interaction

Disease NameRisk Factors
Severe hepatic impairment
Risk of hepatic encephalopathy
Respiratory depression
Can worsen breathing difficulty

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 20-25°C

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.