Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Oliguric phase of renal failure
Age: Adult
Dose: Intravenous infusion – 50-100 g
Duration: in a 24-hour period
Note: Adjust rate of administration to maintain a urine flow of at least 30-50 mL/hr.
Indication: Cerebral oedema, Reduction of raised intraocular pressure
Age: Adult
Dose: Intravenous infusion – 0.25-2 g/kg
Duration: given over 30-60 minutes

Child Dose

Clinical InformationAdministration Information
Indication: Edema
Condition: Intravenous
Dose: Intravenous – 0.25-1 g/kg
Note: initially
Indication: Edema
Condition: Intravenous
Dose: Intravenous – 0.25-0.5 g/kg
Frequency: every 4-6 hours
Note: maintenance dose
Administration
  • Hospital use only
  • Given by IV
Side Effect

Drug Interaction

Drug NameRisk Factors
Ciclosporin
Increased nephrotoxicity

Disease Interaction

Disease NameRisk Factors
Pulmonary congestion
Risk of fluid overload
Pulmonary edema
Can worsen breathing

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Mannitol should be stored at a temperature of 20° to 30°. Exposure to lower temperatures may cause deposition of crystals, which should be dissolved by warming the bottle in hot water for about 30 minutes. Cool to body temperature before using. If all crystals can not be dissolved, the solution should not be used. The content of open containers should be used promptly. Unused contents should be discarded.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.