Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Oral Depression
Age: Adult
Dose: Oral – 75-100 mg/day
Frequency: in 3 or 4 divided doses
Note: Maximum: 150 mg/day in severe depression.
Indication: Oral Depression
Age: Elderly
Dose: Oral – 30-50 mg/day
Frequency: in divided doses

Child Dose

Clinical InformationAdministration Information
Indication: Depression
Age: Adolescent
Dose: Oral – 30-50 mg/day
Frequency: in divided doses
Indication: Nocturnal enuresis
Age: Child: 6-7 yr
Dose: Oral – 10 mg
Frequency: 30 minutes before bedtime
Duration: not greater than 3 months
Administration
  • May be taken with or without food
  • Take at bedtime unless directed otherwise
Side Effect

Drug Interaction

Drug NameRisk Factors
SSRIs, SNRIs, TCAs, Triptans, Fentanyl, Lithium, Tramadol, Tryptophan, Buspirone
Increased risk of serotonin syndrome
Bethanidine, Guanethidine, Debrisoquine, Clonidine
May reduce antihypertensive effect

Disease Interaction

Disease NameRisk Factors
Mania
Can trigger manic episodes
Recent MI
Risk of cardiac complications

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15-30° C. Protect from light and moisture.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.