Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Peptic ulcer Age: Adult Condition: Duodenal ulcer |
Dose: Oral – 20 or 40 mg/day Frequency: once daily in the morning Duration: 4 weeks Note: 40 mg/day is for severe cases |
|
Indication: Peptic ulcer Age: Adult Condition: Gastric ulcer |
Dose: Oral – 20 or 40 mg/day Frequency: once daily in the morning Duration: 8 weeks Note: 40 mg/day is for severe cases |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: GERD Age: less than 1 year |
Dose: Oral – Safety and efficacy not established Note: Safety and efficacy not established |
|
Indication: GERD Age: greater than 1 year |
Dose: Oral – 5 mg Frequency: once daily Note: by mouth (oral) |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Not specified – No dosage adjustment needed. Note: Renal impairment: No dosage adjustment needed. |
Administration
- Take 1 hour before meals
- Swallow capsule whole
Side Effect
- Headache (7%)
- Abdominal pain (5%)
- Diarrhea (4%)
- Nausea (4%)
- Vomiting (3%)
- Flatulence (3%)
- Dizziness (2%)
- Upper respiratory infection (2%)
- Acid regurgitation (2%)
- Constipation (2%)
- Rash (2%)
- Cough (1%)
- Fracture of bone
- osteoporosis-related
- Hepatotoxicity (rare)
- Agranulocytosis
- Anorexia
- Gastric polyps
- Hip fracture
- Alopecia
- Atrophic gastritis
- Interstitial nephritis (rare)
- Pancreatitis (rare)
- Rhabdomyolysis
- Taste perversion
- Abnormal dreams
- Toxic epidermal necrolysis (rare)
- Anaphylaxis
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Diuretics (Chlorothiazide, Chlorthalidone, Hydrochlorothiazide, Indapamide, Metolazone, Bumetanide, Ethacrynic acid, Furosemide, Torsemide, Amiloride, Eplerenone, Spironolactone, Triamterene)
|
Increased risk of hypomagnesaemia
|
|
Warfarin
|
May increase INR and prothrombin time
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep in a dry place away from light and heat. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.