Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Nausea and vomiting Age: Adult |
Dose: Oral – 25 mg Frequency: at night Note: May be increased to 50 or 75 mg at night or to 25 mg twice daily or three times daily, if needed. Maximum: 100 mg daily. |
|
Indication: Prophylaxis of motion sickness Age: Adult |
Dose: Oral – 25 mg Frequency: at night or 1-2 hours before travelling |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Nausea and vomiting Age: 5-10 years |
Dose: Oral – 12.5-37.5 mg Frequency: once daily Note: as teoclate |
|
Indication: Prophylaxis of motion sickness Age: 5-10 years |
Dose: Oral – 12.5 mg Frequency: once daily Note: as teoclate; starting either on the night before long journeys or 1-2 hours before short journeys |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Dose reduction may be required Frequency: Dose reduction may be required. |
Administration
- Can be taken with or without food
- Take at regular intervals
Side Effect
- Neuroleptic Malignant Syndrome (NMS)
- CV effects (eg bradycardia
- tachycardia
- transient HTN
- hypotension
- jaundice
- blood dyscrasias
- extrapyramidal effects
- IV Injection Severe tissue injury (eg gangrene)
- pain and burning
- paralysis
- thrombophlebitis
- severe spasm of distal vessels
- necrosis
- Sedation
- Confusion
- Disorientation
- Blurred vision
- Hallucinations
- Dystonias
- Catatonic states
- Euphoria
- Excitation
- Impotence
- Urinary retention
- Resp depression and apnoea esp in childn
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Aminoglycoside Antibiotics (Gentamicin, Amikacin, Tobramycin, Neomycin, Streptomycin, Paromomycin)
|
Masks ototoxicity
|
|
Alcohol, Hypnotics, Barbiturates, Opioids
|
May enhance sedative effects
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Coma
|
Worsens unconsciousness
|
|
Porphyria
|
Can trigger acute attacks
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store between 15-30° C. Protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.