Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Acute migraine attacks
Age: Adult
Dose: Oral – Initially 10 mg
Frequency: as needed
Note: If ineffective, second dose should not be taken for the same attack. If symptoms recur after initial response, a further dose of 10 mg may be given. Doses should be separated by at least 2 hours. Maximum: 20 mg/24 hours.
Indication: Acute migraine attacks
Age: Adult
Condition: Patient is also taking propanolol
Dose: Oral – 5 mg
Frequency: as needed
Note: Maximum: 10 mg/24 hours. Ensure that the 2 drugs are separated by at least 2 hours.

Child Dose

Clinical InformationAdministration Information
Indication: Acute treatment of migraine with or without aura
Age: less than 6 years
Dose: Oral –
Note: Safety and efficacy not established
Indication: Acute treatment of migraine with or without aura
Age: 6-17 years
Dose: Oral – 5 mg
Frequency: once every 24 hours
Note: by mouth (oral). Efficacy and safety of treatment with more than 1 dose within 24 hours in pediatric patients has not been established. If taking propranolol: Do not administer rizatriptan.

Renal Dose

Clinical InformationAdministration Information
Condition: Mild-moderate renal impairment
Dose: Form – 5 mg
Frequency: Initial dose; further dose of 5 mg may be taken after an interval of at least 2 hours
Note: Maximum 10 mg/24 hours
Condition: Severe renal impairment
Dose: Form – Not specified
Note: Avoid use in severe impairment
Administration
  • Can be taken with or without food
  • Take at onset of migraine
Side Effect

Drug Interaction

Drug NameRisk Factors
Propranolol
Increased serum concentrations
Ergotamine, Methysergide
Increased risk of vasospastic reactions

Disease Interaction

Disease NameRisk Factors
History of MI
Risk of heart attack
Peripheral Vascular Disease
Can worsen circulation

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at 15-30° C.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.