Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Hyperphosphatemia Condition: End-Stage Renal Disease Hemodialysis, Serum PO4 greater than 9 mg/dL (2.91 mmol/L) |
Dose: Oral Tablet – 1600 mg Frequency: every 8 hours with meals Note: Initial dose |
|
Indication: Hyperphosphatemia Condition: End-Stage Renal Disease Hemodialysis, Serum PO4 7.5-9 mg/dL (2.42-2.91 mmol/L) |
Dose: Oral Tablet – 1200-1600 mg Frequency: every 8 hours with meals Note: Initial dose |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Safety and efficacy not established |
Administration
- Take with meals
- Do not chew tablets
Side Effect
- Vomiting (22%)
- Nausea (20%)
- Diarrhea (19%)
- Dyspepsia (16%)
- Nasopharyngitis (14%)
- Limb pain (13%)
- Pruritus (13%)
- Arthralgia (12%)
- Bronchitis (11%)
- Dyspnea (10%)
- Hypertension (10%)
- Abdominal pain (9%)
- Constipation (8%)
- Flatulence (8%)
- Peritonitis (during peritoneal dialysis 8%)
- Hypercalcemia (5-7%)
- Back pain
- Cough
- Headache
- Pyrexia
- Upper respiratory infection
- Pruritus
- Rash
- Intestinal perforation
- Fecal impaction
- Intestinal obstruction
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Ciprofloxacin, Ciclosporin, Mycophenolate, Tacrolimus, Levothyroxine
|
May decrease absorption
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Hypophosphatemia
|
Can lower phosphate further
|
|
Bowel Obstruction
|
Can worsen blockage
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a cool and dry place, protected from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.