Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Oral Toxoplasmosis; Protozoal infections; Cryptosporidiosis; Susceptible infections Age: Adult |
Dose: Oral – 6-9 million units/day Frequency: in 2-3 divided doses |
|
Indication: Oral Toxoplasmosis; Protozoal infections; Cryptosporidiosis; Susceptible infections Age: Adult Condition: severe infections |
Dose: Oral – 15 million units/day Frequency: given in divided doses |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Chemoprophylaxis of congenital toxoplasmosis Age: Child and Neonates |
Dose: Oral – 50 mg/kg Frequency: twice daily |
Administration
- Can be taken with or without food
- Complete full course
Side Effect
- Nausea
- vomiting
- abdominal pain
- diarrhoea
- urticaria
- pruritus
- macular rashes
- Transient paraesthesia may occur
- Pseudomembranous colitis
- anaphylaxis
- neuromuscular blockade
- ventricular arrhythmias
- prolongation of QT interval
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Carbidopa, Levodopa
|
Decreases carbidopa absorption and levodopa concentrations
|
|
Astemizole, Cisapride, Terfenadine
|
Increased risk of ventricular arrhythmias
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a dry place between 15ºC and 30ºC.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.