Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Pre-exposure immunization Age: Adults and Children |
Dose: Intramuscular Injection – 1 ml Frequency: Days 0, 7, 21 or 28 Duration: Followed by a booster dose one year later Note: Thereafter, one injection every 5 years or when the titre is found to be less than 0.5 IU/ml. |
|
Indication: Post-exposure immunization Age: Adults Condition: Non-immunized subjects, standard intramuscular regimen |
Dose: Intramuscular Injection – 1 ml Frequency: Days 0, 3, 7, 14, and 28 (1-1-1-1-1 regimen) |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Rabies Pre-exposure immunization Age: children and adults |
Dose: Intramuscular injection – 1 ml Frequency: Days 0, 7, 21 or 28 Duration: Followed by a booster dose one year later Note: According to the WHO recommendations. Thereafter, one injection every 5 years or when the titre is found to be less than 0.5 IU/ml. |
|
Indication: Rabies Post-exposure immunization Condition: non-immunized subjects |
Dose: Intramuscular injection – 1 ml Frequency: Day 0: 1 injection, Day 3: 1 injection, Day 7: 1 injection, Day 14: 1 injection, Day 28: 1 injection Note: Standard intramuscular (1-1-1-1-1) regimen. In case of severe (WHO category 3) wounds, rabies immunoglobulin should be administered as soon as possible with the first dose of rabies vaccine. |
Administration
- Reconstitute before use
- Give IM in deltoid for adults
Side Effect
- Injection site pain
- soreness
- swelling
- erythema
- itching
- burning (30-74%)
- N/V (5-40%)
- Abdominal pain (5-40%)
- Diarrhea (5-40%)
- Headache (5-40%)
- Fatigue (5-40%)
- Localized enlarged lymph nodes sore throat (5-40%)
- Low grade fever (5-40%)
- Chills (5-40%)
- Muscle ache (5-40%)
- Dizziness (5-40%)
- Malaise (5-40%)
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Immunosuppressants (Cyclosporine, Tacrolimus, Mycophenolate, Azathioprine)
|
May reduce the efficacy of vaccines
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Pre-exposure: Severe fever
|
Postpone vaccination
|
|
Pre-exposure: Progressive chronic diseases
|
May affect immune response
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep out of the reach and sight of children. Store & transport at 2°C to 8°C. Protect from light. Do not keep in the deep freeze.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.