Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Type 2 diabetes mellitus Age: Adult Condition: Insulin-naïve |
Dose: Subcutaneous Injection – 10 units Frequency: once daily Note: Recommended daily starting dose followed by individual dosage adjustments; can be administered at any time of the day, preferably at the same time every day. Can be administered alone or in any combination with oral anti-diabetic medicinal products, GLP-1 receptor agonists and bolus insulin. |
|
Indication: Type 1 diabetes mellitus Age: Adult Condition: Insulin-naïve |
Dose: Subcutaneous Injection – One third to one half of the total daily insulin dose (0.2-0.4 units/kg can be used to calculate initial total daily insulin dose) Frequency: once daily Note: Must be combined with short-/rapid-acting meal-time insulin to cover mealtime insulin requirements; requires subsequent individual dosage adjustments. Preferably administered at the same time every day. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Child |
Dose: Safety and efficacy not established Note: Not recommended |
Administration
- Inject SC once daily
- Inject in thigh, arm or abdomen
Side Effect
- Nasopharyngitis (12.9-23.9%)
- Severe hypoglycemic episode (0.3-12.3%)
- Upper respiratory tract infection (URTI) (8.4-11.9%)
- Headache (8.8-11.8%)
- Diarrhea (6.3%)
- Sinusitis (5.1%)
- Gastroenteritis (5.1%)
- Injection site reactions (3.8%)
- Peripheral edema (0.9-3%)
- Lipodystrophy
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
β-blockers
|
Possible absence of hypoglycaemic warning symptoms
|
|
Corticosteroids (Prednisone, Prednisolone, Methylprednisolone, Dexamethasone, Hydrocortisone), danazol, diazoxide, diuretics, glucagon, isoniazid, phenothiazine derivatives, somatropin, sympathomimetic agents, thyroid hormones, oestrogens, progestins, protease inhibitors, atypical Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole)
|
Decreased hypoglycaemic effect
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Drug Hypersensitivity
|
Risk of allergic reaction
|
|
Hypoglycemia
|
Risk of dangerously low blood sugar
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.