Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Hypertension
Dose: Tablet – 4 mg/5 mg
Frequency: once daily
Note: Taken by mouth with or without food. Adjust dose according to blood pressure goals; wait 7-14 days between titration steps. Not to exceed 14 mg/10 mg once daily.
Indication: Hypertension
Condition: Hepatic impairment
Dose: Tablet – Dosage not specified
Note: There are no data to guide dosing recommendations.

Child Dose

Clinical InformationAdministration Information
Age: Pediatric
Dose: Tablet – No approved pediatric dosage available
Note: No approved pediatric dosage available

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment CrCl less than 30 mL/min
Dose: Not recommended
Note: Renal Impairment CrCl less than 30 mL/min: Not recommended
Condition: Renal Impairment CrCl 30-80 mL/min (mild or moderate renal impairment)
Dose: 7/5 mg
Note: Do not exceed 7/5 mg
Administration
  • Take on empty stomach
  • Take at the same time each day
Side Effect

Drug Interaction

Drug NameRisk Factors
Antihypertensive (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, Propranolol, Metoprolol, Atenolol, Carvedilol, Bisoprolol, Nadolol, Amlodipine, Diltiazem, Verapamil, Nifedipine, Nicardipine, Hydrochlorothiazide, Chlorthalidone, Indapamide, Furosemide, Bumetanide, Torsemide, Spironolactone, Amiloride, Triamterene, Prazosin, Doxazosin, Terazosin, Clonidine, Methyldopa, Hydralazine, Minoxidil), diuretics, vasodilators
Increased hypotensive effects
Lithium
May increase serum levels and toxicity

Disease Interaction

Disease NameRisk Factors
Idiopathic angioedema
Risk of severe swelling
Severe hypotension
Can worsen low blood pressure

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store in a dry place below 25⁰C. Keep the container tightly closed and protect from light.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.