Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Suppression of allergic and inflammatory disorders Age: Adult |
Dose: Intramuscular – 20-80 mg Note: administered via deep intramuscular injection into gluteal muscles |
|
Indication: Symptomatic control for hay fever Age: Adult |
Dose: Intramuscular – 40-100 mg Note: administered via deep intramuscular injection into gluteal muscles |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Suppression of allergic and inflammatory disorders Age: Child Condition: As acetonide |
Dose: Injection – initial 0.11 to 1.6 mg/kg/day Frequency: in 3-4 divided doses Note: deep intramuscular into gluteal muscle; Do not use in premature infants and infants of low birth weight as it contains benzyl alcohol. |
|
Indication: Suppression of allergic and inflammatory disorders Age: Child: 6-12 years |
Dose: Injection – 0.03-0.2 mg/kg Frequency: intramuscular every 1-7 days |
Administration
- For injection: Must be mixed with specified solutions
- For intra-articular use: Requires proper medical supervision
Side Effect
- HPA axis supression
- intracranial hypertension
- Cushing's syndrome
- growth retardation in children
- osteoporosis
- fractures
- Peptic ulceration
- glaucoma
- hyperglycaemia
- GI upsets
- increased appetite
- increased fragility of skin
- behavioural changes
- Acute adrenal insufficiency may be precipitated by infection or trauma in patients on long-term corticosteroid therapy or rapid withdrawal
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Salicylates
|
Lowering of plasma levels
|
|
NSAIDs (Ibuprofen, Naproxen, Diclofenac, Celecoxib, Meloxicam, Indomethacin, Piroxicam, Ketorolac)
|
Increased risk of GI bleeding and ulceration
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Untreated Systemic Infections
|
Can worsen infections
|
|
Hypersensitivity
|
Can cause allergic reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store at controlled room temperature, 20-25°C, avoid freezing and protect from light.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.