Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Vulvar and Vaginal Atrophy in Menopause Age: Adult |
Dose: Oral – 1-2 mg Frequency: once daily Duration: for 3 weeks, followed by 1 week off |
|
Indication: Prevention of osteoporosis Age: Adult |
Dose: Oral – 0.5 mg Frequency: once daily Duration: for 3 weeks, followed by 1 week off |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: Not available Note: No approved pediatric dosage available |
Administration
- Can take with or without food
- Take at same time daily
Side Effect
- Anxiety
- Abdominal cramping
- Amenorrhea
- Bloating
- Breakthrough bleeding
- Breast enlargement
- Breast tenderness
- Delayed ejaculation
- Depression
- Dry mouth
- Headache
- Hypertension
- Impotency
- Influenza
- Leukorrhea
- Melasma
- Muscle cramps
- Nausea
- Nervousness
- Peripheral edema
- Polydipsia
- Pruritus
- Rash
- Swelling
- Spotting
- Syncope
- Toothache
- Vaginal discomfort
- vaginal erosion
- vaginal ulceration
- adherence of the vaginal ring to the vaginal wall (Estring)
- Vomiting
- Weight changes
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
CYP1A2 and CYP3A4 inducers (e.g. aminoglutethimide, carbamazepine, phenobarbital, rifampin)
|
May decrease the effects of estradiol
|
|
Hydrocortisone, prednisolone
|
May enhance effects when used together
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Drug Hypersensitivity
|
Risk of allergic reaction
|
|
Undiagnosed Vaginal Bleeding
|
Risk of missing serious condition
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Store below 30°C and dry place. Keep away from light. Keep out of the reach of children.
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.