Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is an oxytocin receptor antagonist. It reduces uterine contractions. It's used to prevent premature labor.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Must be administered by healthcare professionals • Given as IV infusion • Follow specific dilution instructions • Monitor during administration

Question 3

When should this medicine not be used?

Accepted Answer

• Before 24 weeks gestation • In pre-eclampsia • In placental bleeding • In uterine infections

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• May cause nausea and vomiting • Regular monitoring of contractions and fetal heart rate needed • Use with caution in patients with liver or kidney problems • Not recommended for use beyond 48 hours

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Use only between 24-33 weeks of gestation • No embryo-fetal toxicity shown in studies • No data on fertility and early embryonic development

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• May cause nausea and vomiting • Regular monitoring of contractions and fetal heart rate needed • Use with caution in patients with liver or kidney problems • Not recommended for use beyond 48 hours

Question 7

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For once-daily dosing: If you remember on the same day, take the dose. • For twice-daily dosing: If more than 6 hours until your next dose, take the missed dose. • Take your next dose at the regular time. • If you miss multiple doses, contact your doctor.

Question 8

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Vomiting, headache, dizziness. • Treatment: Symptomatic supportive care.

Question 9

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Nausea, vomiting, headache, dizziness, hot flushes, fast heartbeat, low blood pressure, high blood sugar • What to do: Regular blood pressure monitoring; Blood sugar checking; Report severe headaches; Stay in medical observation; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 10

What is Tocoban 37.5 37.5mg/5ml used for?

Accepted Answer

Tocoban 37.5 37.5mg/5ml (Atosiban) is a pharmaceutical medicine manufactured by Incepta Pharmaceuticals Ltd. in Bangladesh. It is primarily prescribed for Delaying Imminent Pre Term Birth, Premature Labor.

Question 11

What is the active generic component of Tocoban 37.5?

Accepted Answer

The active ingredient in Tocoban 37.5 is Atosiban, belonging to the Drugs Acting On The Uterus drug class.

Question 12

What is the retail price of Tocoban 37.5 37.5mg/5ml in Bangladesh?

Accepted Answer

The official retail price of Tocoban 37.5 37.5mg/5ml (IV Infusion) is ৳2500.00 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 13

What is the recommended dosage for Tocoban 37.5?

Accepted Answer

Standard adult dosage: Intravenous – 0.9 ml (6.75 mg) (once). Pediatric dosage: Tablet – No approved pediatric dosage available. Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 14

Is Tocoban 37.5 safe during pregnancy and breastfeeding?

Accepted Answer

Tocoban 37.5 is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 15

What are the common side effects of Tocoban 37.5?

Accepted Answer

Nausea; vomiting; headache; dizziness; flushes; tachycardia; hypotension; hyperglycaemia; Injection site reactions; insomnia; pruritus; rash; pyrexia; Rarely; uterine haemorrhage and atony;

Clinical Information	Administration Information
Indication: Premature labour Age: Adult Condition: Step 1: Initial bolus	Dose: Intravenous – 0.9 ml (6.75 mg) Frequency: once Duration: over 1 minute Note: Total duration of treatment should not exceed 48 hours. Maximum total dose: 330.75 mg.
Indication: Premature labour Age: Adult Condition: Step 2: Loading infusion	Dose: Intravenous – 24 ml/hour (18 mg/hour) Frequency: continuous Duration: 3 hours Note: Total duration of treatment should not exceed 48 hours. Maximum total dose: 330.75 mg.

Disease Name	Risk Factors
Premature Membrane Rupture >30 Weeks	Risk to fetal health
Intrauterine Growth Problems	Can worsen fetal condition

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources