Question 1

What is this medicine for, and how does it work?

Accepted Answer

This is a combination antibiotic. It inhibits bacterial growth. It is used to treat various bacterial infections.

Question 2

When and how should this medicine be taken?

Accepted Answer

• Dilute each 5mL in 125mL dextrose • For fluid restricted patients use 75mL • Give as IV infusion • Monitor for reactions

Question 3

When should this medicine not be used?

Accepted Answer

• Do not use in first trimester of pregnancy • Do not use in infants under 6 weeks • Do not use in severe liver disease • Do not use if you have blood disorders

Question 4

What precautions should be taken before using this medicine?

Accepted Answer

• Avoid in severe liver failure • Monitor blood disorders • Not for neonates under 6 weeks • Check kidney function • Avoid during pregnancy • Monitor blood counts

Question 5

Is it safe to use this medicine during pregnancy?

Accepted Answer

• Use with caution during pregnancy, especially in the first trimester • Potential risk of birth defects • Use only if benefits outweigh risks

Question 6

Can this medicine be used while breastfeeding?

Accepted Answer

• Avoid in severe liver failure • Monitor blood disorders • Not for neonates under 6 weeks • Check kidney function • Avoid during pregnancy • Monitor blood counts

Question 7

Is this medicine suitable for children and elderly?

Accepted Answer

• Not safe in newborn babies

Question 8

What should be done if a dose is missed?

Accepted Answer

• If you miss a dose, take it as soon as you remember. • However, if it's almost time for your next dose, skip the missed dose. • Never take two doses together. • For twice-daily dosing: If more than 4 hours until your next dose, take the missed dose. • For once-daily dosing: If you remember on the same day, take the dose. • Take your next dose at the regular time. • If you're unsure, contact your doctor or pharmacist.

Question 9

What should be done in case of an overdose?

Accepted Answer

• Symptoms: Vomiting, rash, hematological effects. • Treatment: Blood monitoring, supportive care.

Question 10

What should be done if side effects are experienced?

Accepted Answer

• Common side effects: Skin rash, nausea, vomiting, diarrhea, headache, appetite loss, allergic reactions, liver problems • What to do: Complete full course unless severe reaction; Take with food/water; Avoid sun exposure; Seek immediate help if severe skin reaction or breathing problems occur; Stop taking the medication and seek medical advice if any severe side effect or unusual symptoms occur.

Question 11

What is Aptrim 800mg+160mg used for?

Accepted Answer

Aptrim 800mg+160mg (Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml) is a pharmaceutical medicine manufactured by Apollo Pharmaceutical Laboratories Ltd. in Bangladesh. It is primarily prescribed for Bacterial Infections, Gastrointestinal Tract Infections, Renal & Urinary Tract Infection (UTI), Septicemia, Skin & Wound Infection, Upper & Lower Respiratory Tract Infections.

Question 12

What is the active generic component of Aptrim?

Accepted Answer

The active ingredient in Aptrim is Sulphamethoxazole 200 mg +Trimethoprim 40 mg/ml, belonging to the Sulphonamides & Trimethoprim drug class.

Question 13

What is the retail price of Aptrim 800mg+160mg in Bangladesh?

Accepted Answer

The official retail price of Aptrim 800mg+160mg (Tablet) is ৳2.02 in Bangladesh (prices may vary slightly by pack size and authorized pharmacy).

Question 14

What is the recommended dosage for Aptrim?

Accepted Answer

Standard adult dosage: Intravenous – 960 mg (twice daily). Pediatric dosage: Intravenous – 18 mg/kg (every 12 hours). Always consult a registered physician for individualized dosage adjustments based on clinical assessment.

Question 15

Is Aptrim safe during pregnancy and breastfeeding?

Accepted Answer

Aptrim is classified under Pregnancy Category "Not Assigned". Always consult your healthcare provider or OB/GYN before taking this medication during pregnancy or lactation.

Question 16

What are the common side effects of Aptrim?

Accepted Answer

Allergic myocarditis; erythema multiforme; exfoliative dermatitis; angioedema; drug fever; chills; Henoch-Schoenlein purpura; serum sickness-like syndrome; generalised allergic reactions; generalised skin eruptions; phot

Clinical Information	Administration Information
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections Age: Adult	Dose: Intravenous – 960 mg Frequency: twice daily Note: Severe hepatic impairment: Contraindicated.
Indication: Severe infections Age: Adult	Dose: Intravenous – 2.88 g daily Frequency: in 2 divided doses Note: Severe hepatic impairment: Contraindicated.

Clinical Information	Administration Information
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections Age: Child	Dose: Intravenous – 18 mg/kg Frequency: every 12 hours Note: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections
Indication: Acute exacerbations of chronic bronchitis; Acute otitis media; Urinary tract infections Age: Child Condition: Severe infections	Dose: Intravenous – Up to 27 mg/kg Frequency: every 12 hours Note: Maximum: 1.44 g every 12 hours

Clinical Information	Administration Information
Condition: Renal impairment: Creatinine Clearance less than 15 ml/min	Dose: Dosage Recommendation – Not recommended. Note: Renal impairment: Creatinine Clearance (ml/min) Dosage Recommendation
Condition: Renal impairment: Creatinine Clearance 15-30 ml/min	Dose: Dosage Recommendation – Half the standard dose. Note: Renal impairment: Creatinine Clearance (ml/min) Dosage Recommendation

Drug Name	Risk Factors
ACE Inhibitors (Captopril, Enalapril, Lisinopril, Ramipril, Benazepril, Fosinopril, Quinapril, Perindopril)	May increase risk of hyperkalaemia
Prilocaine	Increased risk of methaemoglobinaemia

Disease Name	Risk Factors
Severe Hepatic Failure	Risk of drug toxicity
Serious Haematological Disorders	Risk of blood disorders

Medicine Overview

Indication

What is this medicine for, and how does it work?

When and how should this medicine be taken?

When should this medicine not be used?

What precautions should be taken before using this medicine?

Is it safe to use this medicine during pregnancy?

Can this medicine be used while breastfeeding?

Is this medicine suitable for children and elderly?

What should be done if a dose is missed?

What should be done in case of an overdose?

What should be done if side effects are experienced?

Adult Dose

Child Dose

Renal Dose

Drug Interaction

Disease Interaction

Pregnancy

Data Sources