Medicine Overview

Indication

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Adult Dose

Clinical InformationAdministration Information
Indication: Insomnia
Age: Adult
Condition: Short-term treatment (maximum 2 weeks) of severe insomnia which is interfering with normal daily life and where other therapies (behavioural and pharmacologic) have failed
Dose: Oral Solution – 430-860 mg (15-30 ml of the 143mg/5ml strength)
Note: Higher doses should not exceed a maximum of 2 g chloral hydrate (70 ml of the 143mg/5ml strength) per dose

Child Dose

Clinical InformationAdministration Information
Indication: Severe insomnia
Age: Children 12 years and over
Condition: Interfering with normal daily life and other therapies (behavioural and pharmacologic) have failed
Dose: Oral – 430-860 mg (15-30 ml of the 143mg/5ml strength)
Duration: maximum 2 weeks
Note: Short-term treatment in children and adolescents with suspected or definite neurodevelopmental disorder. Higher doses should not exceed a maximum of 2 g chloral hydrate (70 ml of the 143mg/5ml strength) per dose.
Indication: Severe insomnia
Age: Children (between 2 and 11 years)
Condition: Interfering with normal daily life and other therapies (behavioural and pharmacologic) have failed
Dose: Oral – 1-1.75 ml/kg of the 143mg/5ml strength
Duration: maximum 2 weeks
Note: Short-term treatment in children and adolescents with suspected or definite neurodevelopmental disorder. The dose should not exceed 1 g chloral hydrate (35 ml of the 143 mg/5ml strength) per dose.

Renal Dose

Clinical InformationAdministration Information
Condition: Renal Impairment
Dose: Renal Dose
Note: Contraindicated in moderate-severe renal impairment
Administration
  • Dilute with water or fruit juice
  • Take at regular intervals
Side Effect

Drug Interaction

Drug NameRisk Factors
Opiates, barbiturates, TCAs, Antipsychotics (Haloperidol, Risperidone, Quetiapine, Olanzapine, Clozapine, Aripiprazole), Antihistamines (Diphenhydramine, Loratadine, Levocetirizine, Cetirizine, Fexofenadine, Hydroxyzine, Bilastin), other sedatives
Enhanced sedative effect
IV furosemide
May cause hot flushes, sweating, and HTN

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.