Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Acute treatment of migraine with or without aura
Age: Adult
Dose: Nasal spray – 2.5 mg
Frequency: initially, at onset of migraine
Note: May increase dose to 5 mg; not to exceed 5 mg per single dose; individual response varies. May repeat dose if migraine has not resolved after 2 hours; not to exceed 10 mg per 24 hours. Safety not established for tablets in the treatment of greater than 3 migraines per 30 days or greater than 4 migraines per 30 days for the intranasal formulation.
Condition: Hepatic impairment
Dose: Nasal spray
Note: Avoid use.

Child Dose

Clinical InformationAdministration Information
Indication: Migraine
Age: less than 12 years
Dose: Nasal spray
Note: Safety and efficacy not established
Indication: Migraine
Age: greater than 12 years
Dose: Nasal spray – 2.5 mg
Frequency: at onset of migraine
Note: Individual response varies, may increase dose to 5 mg; do not exceed 5 mg per single dose
Administration
  • Use one spray in one nostril
  • Wait 2 hours before second dose if needed
Side Effect

Drug Interaction

Drug NameRisk Factors
SSRI, selective serotonin- and norepinephrine-reuptake inhibitors (SNRI)
Increased risk of serotonin syndrome
Cimetidine, quinolone antibacterials, CYP1A2 inhibitors
Increased zolmitriptan concentrations

Disease Interaction

Disease NameRisk Factors
No specific contraindications listed
Monitor for general drug reactions

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage

Details coming soon

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.