Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Adjunct to insulin therapy to improve blood sugar (glycemic) control Age: Adults Condition: Type 1 diabetes mellitus who have failed to achieve adequate glycemic control despite optimal insulin therapy |
Dose: Oral Tablet – 200 mg Frequency: once daily Note: Recommended dose. Take before the first meal of the day. |
|
Indication: Adjunct to insulin therapy to improve blood sugar (glycemic) control Age: Adults Condition: Type 1 diabetes mellitus who have failed to achieve adequate glycemic control despite optimal insulin therapy and tolerating 200 mg |
Dose: Oral Tablet – 400 mg Frequency: once daily Note: The dose may be increased to 400 mg after at least three months if additional glycemic control is needed. |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Renal Dose
| Clinical Information | Administration Information |
|---|---|
|
Condition: Renal impairment |
Dose: Tablet – Not recommended Note: Initiation is not recommended when eGFR is less than 60 mL/min/1.73 m2. Assessment of renal function is recommended prior to initiation and periodically thereafter. |
|
Condition: Persistent renal impairment |
Dose: Tablet – Discontinue Note: Should be discontinued if eGFR is persistently less than 45 mL/min/1.73 m2. |
Administration
- Take once daily before first meal
- Take at same time each day
Side Effect
- genital mycotic infections
- diabetic ketoacidosis and diarrhoea
- Hypotension
- renal impairment
- hepatic impairment
- genital mycotic infections
- Urinary Tract Infection (UTI)
- nausea
- vomiting
- or abdominal pain
- excessive thirst
- constantly feeling tired
- high levels of ketones in urine tests or beta-hydroxybutyrate (BHB) in blood tests
- difficulty breathing/rapid
- deep breathing
- difficulty paying attention
- or confusion
- rapid weight loss
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
No interactions listed
|
-
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
No specific contraindications listed
|
Monitor for general drug reactions
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Details coming soon
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.