Medicine Overview

Adult Dose
Clinical InformationAdministration Information
Indication: Motion Sickness, Nausea and vomiting
Age: Adult
Condition: As hydrochloride
Dose: Oral – 50 mg
Frequency: up to three times daily
Note: Maximum 200 mg/day. For prevention of motion sickness, 1st dose should be given 30 minutes before traveling. May repeat in 4-6 hours if needed.

Child Dose
Clinical InformationAdministration Information
Indication: Motion Sickness, Nausea and vomiting
Age: 6-12 years
Condition: As hydrochloride
Dose: Oral – 25 mg
Frequency: up to three times daily
Note: Not to exceed 75 mg/day. For prevention of motion sickness, 1st dose should be given 30 minutes before traveling.
Indication: Motion Sickness, Nausea and vomiting
Age: greater than 12 years
Dose: Oral – 50 mg
Frequency: may repeat in 4-6 hours if needed
Note: by mouth (oral) taken 30 minutes before departure, up to 200 mg/day
Administration

Administer cyclizine orally as 50 mg tablets or via intramuscular or slow intravenous injection. Oral doses may be taken with or without food up to three times daily; for motion sickness, take 1 to 2 hours before travel. Intravenous injections must be administered slowly over 3 to 5 minutes to minimize risks of hypotension or transient paralysis and may be diluted with 0.9% sodium chloride or 5% glucose. For preoperative prophylaxis, administer the dose 20 minutes before the end of surgery. Use with caution in patients with hepatic impairment, renal impairment, or glaucoma. This medication is generally intended for adults and children over 6 years, with specific dose reductions for pediatric populations.

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Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.