Medicine Overview

Indication

Know Medicine, Follow Guideline

Adult Dose

Clinical InformationAdministration Information
Indication: Uncomplicated urinary tract infections
Age: Adult
Dose: Injection – 250 mg
Frequency: twice daily
Note: Given via intramuscular, intravenous injection over 2-3 minutes or as intravenous infusion.
Indication: Severe Gram-negative infections resistant to gentamicin and tobramycin
Age: Adult
Dose: Injection – 15 mg/kg daily
Frequency: in equally divided doses injected every 8 or 12 hours
Duration: 7-10 days
Note: Maximum: Up to 500 mg every 8 hours in life-threatening infections. Maximum cumulative dose: 15 g. Doses may be given via intramuscular, slow intravenous injection over 2-3 minutes or intravenous infusion.

Child Dose

Clinical InformationAdministration Information
Age: Child
Dose: Intravenous or Intramuscular – 15–22.5 mg/kg/day
Frequency: every 8 hours
Age: Neonate
Condition: Aged less than 7 days
Dose: Intravenous or Intramuscular – 18 mg/kg
Frequency: every 48 hours
Note: Also use this dose for significant asphyxia, indomethacin for patent ductus arteriosus, poor cardiac output, or renal impairment

Renal Dose

Clinical InformationAdministration Information
Condition: Mild renal impairment
Dose: Tablet – 500 mg
Frequency: every 18 hours
Note: Doses should be adjusted based on the patient's CrCl or serum creatinine values
Condition: Moderate renal impairment
Dose: Tablet – 500 mg
Frequency: every 24 hours
Note: Doses should be adjusted based on the patient's CrCl or serum creatinine values
Administration
  • For injection only
  • Given by healthcare professional
Side Effect

Drug Interaction

Drug NameRisk Factors
Amphotericin B
May lead to increased nephrotoxicity and reduced clearance of amikacin
Other nephrotoxic or ototoxic drugs
Increased ototoxic or nephrotoxic effects

Disease Interaction

Disease NameRisk Factors
Perforated Ear Drum
Risk of hearing damage
Myasthenia Gravis
Can worsen muscle weakness

Pregnancy

Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Data Sources

Clinical & regulatory information on this page is compiled from the following government sources:

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.