Medicine Overview
Adult Dose
| Clinical Information | Administration Information |
|---|---|
|
Indication: Uncomplicated premature labour Age: Adult Condition: Starting oral therapy 30-60 minutes before termination of intravenous infusion |
Dose: Oral – 10 mg Frequency: every 2 hours Duration: for 24 hours Note: Maximum oral dose 120 mg daily |
|
Indication: Uncomplicated premature labour Age: Adult Condition: Subsequent therapy |
Dose: Oral – 10-20 mg Frequency: every 4-6 hours Note: According to patient's response. Maximum oral dose 120 mg daily |
Child Dose
| Clinical Information | Administration Information |
|---|---|
|
Age: Pediatric |
Dose: No approved pediatric dosage available Note: No approved pediatric dosage available |
Administration
- Must be administered by healthcare professionals
- Requires careful monitoring
Side Effect
- nausea
- vomiting
- flushing
- sweating
- tremor
- hypokalaemia
- tachycardia
- palpitations
- hypotension (left lateral position throughout infusion to minimize risk)
- uterine bleeding
- pulmonary oedema
- chest pain or tightness
- arrhythmias and salivary gland enlargement
- On prolonged administration for several weeks may cause leucopenia and agranulocytosis
- liver function abnormalities including increased transaminases and hepatitis
- Rarely
- anaphylaxis
- arrhythmia
- pulmonary oedema
- hypokalaemia
Drug Interaction
Drug Interaction
| Drug Name | Risk Factors |
|---|---|
|
Pancuronium, Vecuronium
|
May enhance neuromuscular blockade
|
|
Potassium-depleting drugs
|
May increase risk of hypokalaemia
|
Disease Interaction
Disease Interaction
| Disease Name | Risk Factors |
|---|---|
|
Cardiac Disease
|
Risk of heart complications
|
|
Antepartum Hemorrhage
|
Can worsen bleeding
|
Pregnancy
Pregnancy
Lactation
Special Use
Precaution
Overdose
Pharmacology
Storage
Keep away from the reach of the children. Store in cool & dry place protected from light
Data Sources
Clinical & regulatory information on this page is compiled from the following government sources:
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment.